"Melanopsin Signaling in the Eye"游景威 博士-2012.10.30

时间：2012年10月30日 10:00

地点：脑功能研究所一楼会议室

报告题目：Melanopsin Signaling in the Eye

报告人：游景威 博士

报告人简介：1975获得哈佛大学神经生物学博士学位，1975-1986年先后在斯坦福大学、剑桥大学、UTMB Galveston工作；1986-2004年为Howard Hughes医学研究所研究员，1986年至今任约翰霍普金斯大学神经科学系教授，主要从事视觉和触觉的神经机制研究，发表了150余篇学术论文，其中48篇发表在Nature、Science、Neuron 等顶级学术杂志；获得多个学术奖项。2010年，以其杰出的研究水平和成果，当选为美国科学院院士。

报告简介：Rods and cones not only absorb light for initiating image vision, but also contribute to non-image vision, including circadian photoentrainment, pupillary light reflex, etc. A recent surprising discovery is that ganglion cells, which convey rod/cone signals to the brain, are themselves photosensitive by expressing a visual pigment, melanopsin. These cells, similar to rods, have high signaling efficiency capable of single-photon detection. However, they have an extremely low pigment density (compared to rods and cones). We are studying the phototransduction mechanism in these fascinating, newly-discovered photoreceptors, which does not appear to involve cGMP as in rods and cones